Aug 11, 2025
3 min read
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Our lives have many consistent stable steps, not only slowing but deeper change.
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We have always believed that when we're going out of the end of the year, we are slow and progressive processes.
This is collected by recent instructions and medical assessments, continuing to identify biological aging, in their simplest way, such as "the slow and progressive change of physical function begins in maturity and conclusions with death".
Although this image - or suddenly, suddenly, sudden, sudden, sudden, sudden, sudden, sudden, suddenly, suddenly, sudden, sudden.Suddenly, suddenly, sudden, sudden, sudden, sudden, sudden, sudden, sudden, sudden.
There are challenging linear patterns of this hypothesis and open a new way to understand time -related biological changes.
What was discovered by the laboratory
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Far from finding a soft transformation continuum, they observed an interesting scheme. The biochemical changes associated with aging are concentrated in two moments of cement, about 44 and 60 years of adulthood.
In other words, our molecules - and that's our molecules and organ means that is deeply and synchronized conversion.
The extraordinary thing is that these tips are not due to a type of molecule, but affects proteins, metabolites, lipids, cytokines, hormonal factors, and even epigenetic models, all at the same time.
This provides biological support for widespread sensation, which at a certain time "suddenly becomes greater" and is impressed with physical or mental collapse.
Suddenly
This idea is not very new.2019, is a great customer analysis in the blood in the history of physics: at 34, 1960s and 78 years.
However, in 2024, a new study is more in the analysis of other kinds of molecules other than prote.With this, it is possible to find the two most densely the jumps listed above: one in the middle of the old life, about 44 years, about 60 years later.
When analyzing even more molecules, this work focuses on two jumps that change globally in the body, although they do not exclude that they can be the other later.
What happens in these jumps?
The first time is the right waterfall, the right waterfall, muscle and color carfatie protein.
If this second, before 60 borrow is the task of imitoes and the salad function of the saladance.
Therefore, many have noted that when the effort suddenly is in a difficult time building after a few uncomfortable.
These jumps do not distinguish between men and women and are independent of the reproductive context, such as menopause.At that time, there was some volatility of the intensity of individuals and changes, and common models seem to respond to conventional biology mechanisms.
The molecular reasons
Of course, the dubley because there is no know that some method is found.One of the most studied assumption indicates that when the older cell is experiment to reach a specific border of the old cells, chain response.
In addition, epigenetics - "signs" that regulate genes - also suffers from mass reconfiguration in these periods, which causes the activation or inactivation of hundreds of gene genes.
After that, in the atmosphere of access to the highlights, nad⁺, food and old energy methods of powerful magnetic magazines.
All of these things, which can be briefly or distant, have its own impacts in everyday life.
The practical impact of this is important.On the other hand, it provides convincing information that is the most but "I feel sudden."
On the other hand, this shows that these critical moments can be hit and prevent the window.If we know that our biological system will soon be subject to major changes, we can anticipate that it is receiving more metabolic health, cardiovascular or immunity just before and during the key period.
Looking forward to the future
Although there are still many open problems, it will be possible to define the detailed reasons and mechanisms of the third jump around 78 years suggested in 2019, the truth in these patterns allows us to look at aging with other eyes.
Since longitudinal studies are expanded and the molecular analysis layer are integrated, we can also appreciate exactly if a single biological jump occurs.
However, we have already known that our lives do not slow down, but a list of steady measures are discontinued with a deep change.So it can be the best old age secret to prepare for jump when it comes with it.
And as the short Celts sing, "Sometimes they have time suddenly you are old."
* O le francisco josé esteban diz o se polofesa o le sela biology, jaén iunivesite.
* This article was originally published in the conversation.
